GH Secretagogues
GHRP-6
Also published as Growth hormone releasing peptide 6
The first of the growth hormone releasing peptides and the compound that led to the discovery of the ghrelin receptor before ghrelin itself was identified. It produces the strongest appetite response of the class.
Where it came from
Developed by Cyril Bowers in the 1980s. The search for its endogenous ligand ended with the identification of ghrelin in 1999.
What the literature examines
- Growth hormone release and ghrelin receptor pharmacology
- Appetite stimulation in animals and humans
- Cytoprotection and tissue repair, in a substantial Cuban research programme at CIGB
- Cardiac and hepatic injury models
State of the evidence
Human endocrine studies exist from the 1990s. The Cuban cytoprotection work has progressed further than most Western readers realise.
What a buyer should know
Marked appetite stimulation is the defining practical feature, and it is often presented as a benefit without noting it is a systemic ghrelin receptor effect. It raises cortisol and prolactin alongside growth hormone.
Handling and stability
Lyophilised, water soluble.
Sequence
His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
Read it yourself
We do not publish a curated citation list, because a hand picked list of papers is a sales tool. These links run a live query against the public databases, so you see everything, including the results that do not suit us.
Supplied for laboratory research use only. Nothing on this page is a dose, a protocol or a claim of effect in humans, and nothing here is medical advice. Read our research use policy.